6vvx_CDFM : 3D-footprint complex

structure name	MYCOBACTERIUM TUBERCULOSIS WT RNAP TRANSCRIPTION INITIATION INTERMEDIATE STRUCTURE WITH SORANGICIN
source	MYCOBACTERIUM TUBERCULOSIS
experiment	NMR
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6vvx_C interface=369,370,373,374, nsvpgapnrvsfaklreplevpglldvqtdsfewligsprwresaaergdvnpvggleevlyelspiedfsgsmslsfsdprfddvkapvdeckdkdmtyaaplfvtaefinnntgeiksqtvfmgdfpmmtekgtfiingtervvvsqlvrspgvyfdetidkstdktlhsvkvipsrgawlefdvdkrdtvgvridrkrrqpvtvllkalgwtseqiverfgfseimrstlekdntvgtdealldiyrklrpgepptkesaqtllenlffkekrydlarvgrykvnkklglhvgepitsstlteedvvatieylvrlhegqttmtvpggvevpvetddidhfgnrrlrtvgeliqnqirvgmsrmeRVvrERmttqdveaitpqtlinirpvvaaikeffgtsqlsqfmdqnnplsglthkrrlsalgpgglsreraglevrdvhpshygrmcpietpegpnigligslsvyarvnpfgfietpyrkvvdgvvsdeivyltadeedrhvvaqanspidadgrfveprvlvrrkageveyvpssevdymdvsprqmvsvatamipflehddanralmganmqrqavplvrseaplvgtgmelraaidagdvvvaeesgvieevsadyitvmhdngtrrtyrmrkfarsnhgtcanqcpivdagdrveagqviadgpctddgemalgknllvaimpweghnyedaiilsnrlveedvltsihieeheidardtklgaeeitrdipnisdevladldergivrigaevrdgdilvgkvtpkgeteltpeerllraifgekarevrdtslkvphgesgkvigirvfsrededelpagvnelvrvyvaqkrkisdgdklagrhgnkgvigkilpvedmpfladgtpvdiilnthgvprrmnigqilethlgwcahsgwkvdaakgvpdwaarlpdelleaqpnaivstpvfdgaqeaelqgllsctlpnrdgdvlvdadgkamlfdgrsgepfpypvtvgymyimklhhlvddkiharstgpysmitqqplggkaqfggqrfgemecwamqaygaaytlqelltiksddtvgrvkvyeaivkgenipepgipesfkvllkelqslclnvevlss > 6vvx_D interface=391,398, gamldvnffdelriglataedirqwsygevkkpetinyrtlkpekdglfcekifgptrdwecycgkykrvrfkgiicercgvevtrakvrrermghielaapvthiwyfkgvpsrlgylldlapkdlekiiyfaayvitsvdeemrhnelstleaemaverkavedqrdgelearaqkleadlaeleaegakadarrkvrdggeremrqirdraqreldrlediwstftklapkqlivdenlyrelvdrygeyftgamgaesiqklienfdidaeaeslrdvirngkgqkklralkrlkvvaafqqsgnspmgmvldavpvippelrpmvqldggrfatsdlndlyrrvinrnnrlkrlidlgapeiivnnekrmlqesvdalfdngrrgRpvtgpgNrplkslsdllkgkqgrfrqnllgkrvdysgrsvivvgpqlklhqcglpklmalelfkpfvmkrlvdlnhaqniksakrmverqrpqvwdvleeviaehpvllnraptlhrlgiqafepmlvegkaiqlhplvceafnadfdgdqmavhlplsaeaqaearilmlssnnilspasgrplamprldmvtglyylttevpgdtgeyqpasgdhpetgvysspaeaimaadrgvlsvrakikvrltqlrppveieaelfghsgwqpgdawmaettlgrvmfnellplgypfvnkqmhkkvqaaiindlaerypmivvaqtvdklkdagfywatrsgvtvsmadvlvpprkkeildhyeeradkvekqfqrgalnhdernealveiwkeatdevgqalrehypddnpiitivdsgatgnftqtrtlagmkglvtnpkgefiprpvkssfregltvleyfinthgarkgladtalrtadsgyltrrlvdvsqdvivrehdcqtergivvelaerapdgtlirdpyietsayartlgtdavdeagnvivergqdlgdpeidallaagitqvkvrsvltcatstgvcatcygrsmatgklvdigeavgivaaqsigepgtqltmtgglprvqelfearvprgkapiadvtgrvrledgerfykitivpddggeevvydkiskrqrlrvfkrvlsdgdhvevgqqlmegsadphevlrvqgprevqihlvrevqevyraqgvsihdkhievivrqmlrrvtiidsgsteflpgslidraefeaenrrvvaeggepaagrpvlmgitkaslatdswlsaasfqettrvltdaaincrsdklnglkenviigklipagtginryrniavqpteearaaa > 6vvx_F interface=18,20,21,127,128,131,133,136,137,138,140,141,142,144,145,149,162,163,166,173,176,291,292,293,294,296,297, sealrqarkdaeltasaDsVRaylkqigkvallnaeeevelakrieaglyatqlmtelsergeklpaaqrrdmmwicrdgdraknhlleanlrlvvslakrytgrgmafldliqegnlgliravekFDytKgYkfSTYaTWWiRQaitRamadqartiripVHmvEvinklgRiqRellqdlgreptpeelakemditpekvleiqqyarepisldqtigdegdsqlgdfiedseavvavdavsftllqdqlqsvldtlsereagvvrlrfgltdgqprtldeigqvygvTRERiRQiesktmsklrhpsrsqvlrdyl > 6vvx_M interface=84,85, ifkvgdtvvyphhgaalveaietrtikgeqkeylvlkvaqgdltvrvpaenaeyvgvrdvvgqegldkvfqvlraphteeptnWSrrykanleklasgdvnkvaevvrdlwrrdqerglsagekrmlakarqilvgelalaestddakaetildevlaa
interface signature	RVER/RN/DVRFDKYSTYTWWRQRVHERRTRERRQ/WS

Estimated binding specificities ?

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# IC=20.718 IC/col=0.609 n_of_columns=34

specificity:

A |   0  10   0   0   0  24   0  96  96  24  69  24  96  24  24  24  24  24  24  24  24  24  24  24  24  24  80   0   0   0  96  80   0  81
C |   0   0  96   0   0  24   0   0   0  24  12  24   0  24  24  24  24  24  24  24  24  24  24  24  24  24   5   0   0  96   0   5   0   5
G |   0  74   0  96   0  24   0   0   0  24  10  24   0  24  24  24  24  24  24  24  24  24  24  24  24  24   5  96   0   0   0   6  96   5
T |  96  12   0   0  96  24  96   0   0  24   5  24   0  24  24  24  24  24  24  24  24  24  24  24  24  24   6   0  96   0   0   5   0   5

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updated Sat Dec 16 19:44:16 2023