6vvs_FT : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A MYCOBACTERIUM SMEGMATIS RNA POLYMERASE TRANSCRIPTION INITIATION COMPLEX WITH ANTIBIOTIC SORANGICIN
reference	Campbell et al. Proc.Natl.Acad.Sci.USA 117 30423 2020
experiment	X-ray (resolution=3.11, R-factor=?)
structural superfamily	C-terminal domain of RNA polymerase alpha subunit;
reference complex	5tw1_T
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6vvs_F interface=126,127,130,133,134,147,148,151,276,277,278,279,281,282, sadsvraylkqigkvallnaeeevelakrieaglyatqklaelaekgeklpvqqrrdmqwicrdgdraknhlleanlrlvvslakrytgrgmafldliqegnlgliravekfdytkgykfstyatWWirQaiTRamadqartiripVHmvEvinklgriqrellqdlgreptpeelakemditpekvleiqqyarepisldqtigdegdsqlgdfiedseavvavdavsftllqdqlqsvletlsereagvvrlrfgltdgqprtldeigqvygvTRERiRQiesktmsklrhpsrsqvlrdyld > 6vvs_T interface=9, iddldltvRsynclkregvhtvgelvartesdlldirnfgqksidevkiklhq
interface signature	WWQTRVHETRERRQ/R

Estimated binding specificities ?

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# IC=12.836 IC/col=0.513 n_of_columns=25

specificity:

A |   9   0   6   0  96   0  68  24  24  24  24  24  24  24  24  24  24  24  24   6  24   0   0   0   0
C |  75   0  16   0   0  96   9  24  24  24  24  24  24  24  24  24  24  24  24   9  24   0   0  96   0
G |   6   0   6  96   0   0   6  24  24  24  24  24  24  24  24  24  24  24  24   6  24   0  96   0   0
T |   6  96  68   0   0   0  13  24  24  24  24  24  24  24  24  24  24  24  24  75  24  96   0   0  96

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updated Sat Dec 16 19:43:20 2023