interface graph thumbnail
legend  pdf

structure nameHIV-1 WILD-TYPE REVERSE TRANSCRIPTASE-DNA COMPLEX WITH (-)-3TC-TP
reference'Commun 2 469 2019 Human immunodeficiency virus type 1 group M subtype B (isolate HXB2)
experimentX-ray (resolution=2.59, R-factor=?)
structural superfamilyDNA/RNA polymerases;Ribonuclease H-like;
reference complex5j2m_B 7ozw_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureIPYMRRQ/VMGSP

Estimated binding specificities ?

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# IC=3.968 IC/col=0.233 n_of_columns=17 specificity:   
A |   0   0  11  24  24  24  24  24  24  24  24  24  24  24  24  67  11
C |   0   0  67  24  24  24  24  24  24  24  24  24  24  24  24   9  67
G |  96  96   9  24  24  24  24  24  24  24  24  24  24  24  24  11   9
T |   0   0   9  24  24  24  24  24  24  24  24  24  24  24  24   9   9
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updated Sat Dec 16 19:07:21 2023