interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF DNMT3B-DNMT3L IN COMPLEX WITH CPGPT DNA
(DNA CYTOSINE-5-METHYLTRANSFERASE 3B)
referenceZhang et al. 'Nat 11 3355 2020
sourceHOMO SAPIENS
experimentX-ray (resolution=3.00, R-factor=0.219)
structural superfamilyS-adenosyl-L-methionine-dependent methyltransferases;
sequence familyC5 cytosinespecific DNA methylase 740;
multimeric complexes6kda_AD 6kdb_AD 6u8p_AD 6u8v_AD 6u8w_AD 6u8x_AD 6u90_AD 6u91_AD
reference complex6kdb_D
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNVPTKSN

Estimated binding specificities ?

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# IC=3.142 IC/col=0.786 n_of_columns=4 specificity:   
A |  13   0  13   0
C |  13   0  13   0
G |  57  96  16   0
T |  13   0  54  96
scan!

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updated Mon Dec 18 18:21:24 2023