6pw2_ABCD : 3D-footprint complex

structure name	STRUCTURAL BASIS FOR COOPERATIVE BINDING OF EBNA1 TO THE EPSTEIN-BARR VIRUS DYAD SYMMETRY MINIMAL ORIGIN OF REPLICATION
reference	Lieberman et al. J.Virol. 93 ? 2019
source	Epstein-Barr virus (strain B95-8) / Epstein-Barr virus (strain B95-8) / Epstein-Barr virus (strain B95-8) / Epstein-Barr virus (strain B95-8) / Epstein-Barr virus (strain B95-8) / Epstein-Barr virus (strain B95-8) / Epstein-Barr virus (strain B95-8) / Epstein-Barr virus (strain B95-8)
experiment	X-ray (resolution=3.01, R-factor=?)
structural superfamily	Viral DNA-binding domain;
reference complex	7u1t_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6pw2_A interface=1,4,5,9,17,54,55,58,59,62, KggWFgkhRgqggsnpKfeniaeglrallarshverttdegtwvagvfvyggsKTslYNlrRgtalaipqcrltplsrlpfgmapgpgpqpgplresivcyfmvflqthifaevlkdaikdlvmtkpaptcnirvtvcsfddgvdlp > 6pw2_B interface=1,4,5,9,17,54,55,58,59, KggWFgkhRgqggsnpKfeniaeglrallarshverttdegtwvagvfvyggsKTslYNlrrgtalaipqcrltplsrlpfgmapgpgpqpgplresivcyfmvflqthifaevlkdaikdlvmtkpaptcnirvtvcsfddgvdlp > 6pw2_C interface=4,5,9,17,54,55,58,59,62, kggWFgkhRgqggsnpKfeniaeglrallarshverttdegtwvagvfvyggsKTslYNlrRgtalaipqcrltplsrlpfgmapgpgpqpgplresivcyfmvflqthifaevlkdaikdlvmtkpaptcnirvtvcsfddgvdlp > 6pw2_D interface=1,4,5,9,17,54,55,58, KggWFgkhRgqggsnpKfeniaeglrallarshverttdegtwvagvfvyggsKTslYnlrrgtalaipqcrltplsrlpfgmapgpgpqpgplresivcyfmvflqthifaevlkdaikdlvmtkpaptcnirvtvcsfddgvdlp
interface signature	KWFRKKTYNR/KWFRKKTYN/WFRKKTYNR/KWFRKKTY

Estimated binding specificities ?

readout + contact

# IC=24.536 IC/col=0.682 n_of_columns=36

specificity:

A |   0  92   0  90   0  24  24  24  24  24   7   1   0  24   4   0   0  24  24  24   1   0   0  24  90  96  24  71  24  24  24   7   0   0  90   4
C |   0   0   0   1   4  24  24  24  24  24   9  90   0  24  86  96  96  24  24  24   4   0   0  24   1   0  24  15  24  24  24   5  90   0   5   1
G |  96   1   0   4  92  24  24  24  24  24  67   4   0  24   3   0   0  24  24  24  90  96  94  24   1   0  24   5  24  24  24  83   0   0   1   1
T |   0   3  96   1   0  24  24  24  24  24  13   1  96  24   3   0   0  24  24  24   1   0   2  24   4   0  24   5  24  24  24   1   6  96   0  90

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updated Sat Dec 16 16:26:45 2023