6kdn_CD : 3D-footprint complex

structure name	HIV-1 REVERSE TRANSCRIPTASE WITH Q151M/Y115F/F116Y:DNA:DGTP TERNARY COMPLEX
reference	Hattori et al. 'Sci 10 3021 2020
source	HUMAN IMMUNODEFICIENCY VIRUS 1 / HUMAN IMMUNODEFICIENCY VIRUS TYPE 1
experiment	X-ray (resolution=2.30, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	6kdn_B 7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6kdn_C interface=24,61,63,74,76,78,94,157,183,184,265,448,475,501, pispietvpvklkpgmdgpkvkqWplteekikalveictemekegkiskigpenpyntpvFaIkkkdstkwrkLvDfRelnkrtqdfwevqlgIphpaglkqkksvtvldvgdafysvpldkdfrkytaftipsinnetpgiryqynvlpmgwkgsPaifqssmtkilepfrkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwgfttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklNwasqiyagikvrqlskllrgtkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwyqlekepiigaetfyvdgaanRetklgkagyvtdrgrqkvvpltdttnQktelqaihlalqdsglevnivtdsqYalgiiqaqpdkseselvsqiieqlikkekvylawvpahkgiggneqvdklvs > 6kdn_D interface= ietvpvklkpgmdgpkvkqwpltEekikalveictemekegkiskigpenpyntpvfaikKkDstkwrklvdfReLnKrtqdfwevqlgiphpAglkqkksvtvldvgdayfsvpldkdfrkytaftipsinnetpgiryqynvlpqgwkgspaifQssmtkilepfrkqnpdiviyqymddLYvgsdleigqhrtkieelrqhllrwggyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiyagikvrqlskllrgTkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwy
interface signature	WFILDRIPYMNRQY/EKDRLKAQLYT

Estimated binding specificities ?

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# IC=11.139 IC/col=0.338 n_of_columns=33

specificity:

A |   0   0   5   0  24   5  24  24  24  24  24  24  24  24  24   5  24   0   5  24  24  24  24  24  24  24  24  24  24  24   5   0   6
C |   0  96   5  96  24  80  24  24  24  24  24  24  24  24  24   5  24   0   6  24  24  24  24  24  24  24  24  24  24  24   6   0  80
G |   0   0  81   0  24   5  24  24  24  24  24  24  24  24  24   5  24   0  80  24  24  24  24  24  24  24  24  24  24  24  80  96   5
T |  96   0   5   0  24   6  24  24  24  24  24  24  24  24  24  81  24  96   5  24  24  24  24  24  24  24  24  24  24  24   5   0   5

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updated Sat Dec 16 12:45:17 2023