6kdk_AB : 3D-footprint complex

structure name	HIV-1 REVERSE TRANSCRIPTASE WITH Q151M/Y115F/F116Y:DNA:DCTP TERNARY COMPLEX
reference	Hattori et al. 'Sci 10 3021 2020
source	HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 / HUMAN IMMUNODEFICIENCY VIRUS 1
experiment	X-ray (resolution=2.56, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	6kdn_B 7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6kdk_A interface=24,61,74,76,78,94,151,157,183,184,265,448, pispietvpvklkpgmdgpkvkqWplteekikalveictemekegkiskigpenpyntpvFaikkkdstkwrkLvDfRelnkrtqdfwevqlgIphpaglkqkksvtvldvgdafysvpldkdfrkytaftipsinnetpgiryqynvlpMgwkgsPaifqssmtkilepfrkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwgfttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklNwasqiyagikvrqlskllrgtkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwyqlekepiigaetfyvdgaanRetklgkagyvtdrgrqkvvpltdttnqktelqaihlalqdsglevnivtdsqyalgiiqaqpdkseselvsqiieqlikkekvylawvpahkgiggneqvdklvs > 6kdk_B interface=248, ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkqkksvtvldvgdayfsvpldkdfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymddlyvgsdleigqhrtkieelrqhllrwggyelhpdkwtvqpivlpekdswtvndiqklvgklnwasQiyagikvrqlskllrgtkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwy
interface signature	WFLDRIMPYMNR/Q

Estimated binding specificities ?

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# IC=8.472 IC/col=0.257 n_of_columns=33

specificity:

A |   0   0  24   0  24  24  24  24  24  24  24  24  24  24  24   0  24   0  24  24  24  24  24  24  24  24  24  24  24  24  13   0  16
C |   0   0  24  96  24  24  24  24  24  24  24  24  24  24  24   0  24   0  24  24  24  24  24  24  24  24  24  24  24  24  13   0  13
G |   0  96  24   0  24  24  24  24  24  24  24  24  24  24  24   0  24   0  24  24  24  24  24  24  24  24  24  24  24  24  57  96  54
T |  96   0  24   0  24  24  24  24  24  24  24  24  24  24  24  96  24  96  24  24  24  24  24  24  24  24  24  24  24  24  13   0  13

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updated Sat Dec 16 12:43:03 2023