6k1k_C : 3D-footprint complex

3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.

Dendrogram of similar interfaces ?

matrix format

structure name	HUMAN NUCLEOSOME CORE PARTICLE WITH H2A.X S139E VARIANT (HISTONE H2AX)
reference	De Falco et al. 'Nat 10 5751 2019
source	HOMO SAPIENS
experiment	X-ray (resolution=2.20, R-factor=0.232)
structural superfamily	Histone-fold;
sequence family	Core histone H2A/H2B/H3/H4;
multimeric complexes	6k1i_ABCDEFGH 6k1j_ABCDEFGH 6k1k_ABCDEFGH
redundant complexes	6k1i_G 6k1j
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6k1k_C interface=29,111, aksrssraglqfpvgrvhrllrkghyaeRvgagapvylaavleyltaeilelagnaardnkktriiprhlqlairndeelnkllggvtiaqggvlpniqavllpkktsatV

  
  ------RT                                               +1u35_G    
                           +-----------------------------1 
  ------RT               +-2                             +7lyb_G    
                         ! ! 
  ------RA             +-3 +-----------------------------6t7a_C    
                       ! ! 
  RAETRT--           +-4 +-----------------------------4ne1_p    
                     ! ! 
  ------RT         +-5 +-----------------------------7wlr_E    
                   ! ! 
  ------RT       +-6 +-----------------------------7zs9_e    
                 ! ! 
  ------RT     --7 +-----------------------------7lya_E    
                 ! 
  --IT--RA       +-----------------------------7k78_E

home
updated Tue Dec 19 13:24:26 2023