6edb_B : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF SRY.HCGAS-21BP DSDNA COMPLEX (SEX-DETERMINING REGION Y PROTEIN,CYCLIC GMP-AMP SYNTHASE)
reference	Glickman et al. Proc.Natl.Acad.Sci.USA 116 11946 2019
source	HOMO SAPIENS
experiment	X-ray (resolution=3.21, R-factor=0.260)
structural superfamily	HMG-box;
sequence family	HMG high mobility group box;
multimeric complexes	6edb_AB
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6edb_B interface=2,5,7,8,15,27,31, kRpmNaFIvwsrdqRrkmalenprmrNseiSkqlgyqwkmlteaekwpffqeaqklqamhrekypny
interface signature	RNFIRNS

Estimated binding specificities ?

readout + contact

# IC=2.674 IC/col=0.669 n_of_columns=4

specificity:

A |  13  78   7   1
C |  56   6   7   2
G |  13   6   7   1
T |  14   6  75  92

scan!

Dendrogram of similar interfaces ?

matrix format

  
  RGNTFTMART--NGRTSA--   L              +----------------------7m5w_A    
                                 +------2 
  RCNAFTIARG--NC--SALT   L       !      !         +------------2gzk_A    
                               +-3      +---------1 
  RTNGFTIARA--NASGST--   L     ! !                +------------1j46_A    
                             +-4 ! 
  RCNGFTMARTHTNG--ST--   L   ! ! +-----------------------------6t90_L    
                           --5 ! 
  RCNTFTMARAHGNAACST--   L   ! +-----------------------------4euw_A    
                             ! 
  RTNTFTMARA--NGACST--   L   +-----------------------------4s2q_D

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updated Thu Dec 22 23:14:19 2022