6c31_EFGH : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF TETR FAMILY PROTEIN RV0078 IN COMPLEX WITH DNA
reference	Hsu et al. MBio 9 ? 2018
source	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) / Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) / Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) / Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) / Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) / Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) / Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) / Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
experiment	X-ray (resolution=3.00, R-factor=?)
structural superfamily	Homeodomain-like;Tetracyclin repressor-like, C-terminal domain;
reference complex	6c31_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6c31_E interface=3,33,42,43,47,48, rtQeersaatrealitgarklwglrgyaevgtPeiateagvTRgamYHqfadkaalfrdvvevveqdvmarmatlvaasgaatpadairaavdawlevsgdpevrqlilldapvvlgwagfrdvaqryslgmteqliteairagqlarqpvrplaqvligaldeaamfiataddpkrarretrqvlrrlidgmln > 6c31_F interface=3,42,43,47,48, rtQeersaatrealitgarklwglrgyaevgtpeiateagvTRgamYHqfadkaalfrdvvevveqdvmarmatlvaasgaatpadairaavdawlevsgdpevrqlilldapvvlgwagfrdvaqryslgmteqliteairagqlarqpvrplaqvligaldeaamfiataddpkrarretrqvlrrlidgmln > 6c31_G interface=43,47, rtqeersaatrealitgarklwglrgyaevgtpeiateagvtRgamYhqfadkaalfrdvvevveqdvmarmatlvaasgaatpadairaavdawlevsgdpevrqlilldapvvlgwagfrdvaqryslgmteqliteairagqlarqpvrplaqvligaldeaamfiataddpkrarretrqvlrrlidgmln > 6c31_H interface=32,42,46,47, tqeersaatrealitgarklwglrgyaevgtPeiateagvtRgamYHqfadkaalfrdvvevveqdvmarmatlvaasgaatpadairaavdawlevsgdpevrqlilldapvvlgwagfrdvaqryslgmteqliteairagqlarqpvrplaqvligaldeaamfiataddpkrarretrqvlrrlidgmln
interface signature	QPTRYH/QTRYH/RY/PRYH

Estimated binding specificities ?

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# IC=11.075 IC/col=0.651 n_of_columns=17

specificity:

A |  89   0  10  24  24   0  73   0   5  24   3   0  10  24  24  22   2
C |   0  96  70  24  24  96   0   0   2  24   0   0  52  24  24   7  10
G |   5   0   9  24  24   0   1  96   6  24   0  96  12  24  24  62   4
T |   2   0   7  24  24   0  22   0  83  24  93   0  22  24  24   5  80

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updated Sat Dec 16 08:37:12 2023