6avm_AB : 3D-footprint complex

structure name	STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) TERNARY COMPLEX WITH A DOUBLE STRANDED DNA AND AN INCOMING D4TTP AT PH 9.5 WITH CROSS- LINKING TO SECOND BASE TEMPLATE OVERHANG
reference	Martinez et al. 'Protein 28 587 2019
experiment	X-ray (resolution=2.50, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	5d3g_B 7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6avm_A interface=96,185,267,450,477, mvpispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfackkkdstkwrklvdfrelnkrtqdfwevqlgIphpaglkkkksvtvldvgdayfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdiviyqYmddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklNwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepivgaetfyvdgaanRetklgkagyvtnkgrqkvvpltnttnQktelqaiylalqdsglevnivtdsqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahkgiggneqvdklvs > 6avm_B interface= pietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaGlkkkksvtvldvgdayfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdiviyqymddlYvgsdleigqhrtkieelrqhllrwpflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlsklLrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyq
interface signature	IYNRQ/GYL

Estimated binding specificities ?

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# IC=2.709 IC/col=0.159 n_of_columns=17

specificity:

A |   9   0  24  24  24  24  24  24  24  24  24  24  24  24  24  76  19
C |   9   0  24  24  24  24  24  24  24  24  24  24  24  24  24   9  57
G |  67  96  24  24  24  24  24  24  24  24  24  24  24  24  24   2   9
T |  11   0  24  24  24  24  24  24  24  24  24  24  24  24  24   9  11

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updated Sat Dec 16 08:17:19 2023