6anq_CD : 3D-footprint complex

structure name	STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) TERNARY COMPLEX WITH A DOUBLE STRANDED DNA AND AN INCOMING D4TTP AT PH 8.5
reference	Martinez et al. 'Protein 28 587 2019
experiment	X-ray (resolution=2.59, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	5d3g_B 7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6anq_C interface=96,185,450,477, mvpispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfackkkdstkwrklvdfrelnkrtqdfwevqlgIphpaglkkkksvtvldvgdayfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdiviyqYmddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepivgaetfyvdgaanRetklgkagyvtnkgrqkvvpltnttnQktelqaiylalqdsglevnivtdsqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahkgiggneqvdklvs > 6anq_D interface= pietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaGlkkkksvtvldvgdayfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdiviyqymddlYvgsdleigqhrtkieelrqhllrwgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyartndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyq
interface signature	IYRQ/GY

Estimated binding specificities ?

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# IC=2.660 IC/col=0.166 n_of_columns=16

specificity:

A |   0   9  24  24  24  24  24  24  24  24  24  24  24  24   7  53
C |   7   7  24  24  24  24  24  24  24  24  24  24  24  24   0  14
G |  88  73  24  24  24  24  24  24  24  24  24  24  24  24  81  22
T |   1   7  24  24  24  24  24  24  24  24  24  24  24  24   8   7

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updated Sat Dec 16 08:13:16 2023