interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF XCAS9 IN COMPLEX WITH SGRNA AND TARGET DNA (AAG PAM)
(DNA Nuclease)
referenceHuang et al. 'Cell 29 183 2019
sourceStreptococcus pyogenes
experimentX-ray (resolution=3.00, R-factor=0.232)
multimeric complexes7v59_BE
reference complex6vpc_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKRR

Estimated binding specificities ?

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# IC=3.101 IC/col=0.775 n_of_columns=4 specificity:   
A |  54  96   0  13
C |  16   0   0  13
G |  13   0  96  16
T |  13   0   0  54
scan!

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updated Mon Dec 18 14:22:50 2023