5xn2_AB : 3D-footprint complex

structure name	HIV-1 REVERSE TRANSCRIPTASE Q151M:DNA:DGTP TERNARY COMPLEX
reference	Yasutake et al. 'Sci 8 1624 2018
source	HUMAN IMMUNODEFICIENCY VIRUS 1
experiment	X-ray (resolution=2.38, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	6kdn_B 7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5xn2_A interface=22,23,59,61,72,76,92,113,181,182,446, spietvpvklkpgmdgpkvkqWPlteekikalveictemekegkiskigpenpyntpvFaIkkkdstkwrkLvdfRelnkrtqdfwevqlgIphpaglkqkksvtvldvgdaYfsvpldkdfrkytaftipsinnetpgiryqynvlpmgwkgspaifqssmtkilepfrkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwgfttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiyagikvrqlskllrgtkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwyqlekepiigaetfyvdgaanRetklgkagyvtdrgrqkvvpltdttnqktelqaihlalqdsglevnivtdsqyalgiiqaqpdkseselvsqiieqlikkekvylawvpahkgiggneqvdklvs > 5xn2_B interface=246,249, pietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkqkksvtvldvgdayfsvpldkdfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymddlyvgsdleigqhrtkieelrqhllrwggyelhpdkwtvqpivlpekdswtvndiqklvgklnWasQiyagikvrqlskllrgtkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwy
interface signature	WPFILRIYYMR/WQ

Estimated binding specificities ?

contact

# IC=8.933 IC/col=0.271 n_of_columns=33

specificity:

A |   0   0  16   9  24  24  24  24  24  24  24  24  24  24  24   0  24   0  24  24  24  24  24  24  24  24  24  24  24  24   8   0  13
C |   0  96  13  75  24  24  24  24  24  24  24  24  24  24  24   0  24   0  24  24  24  24  24  24  24  24  24  24  24  24   6   0  68
G |   0   0  61   6  24  24  24  24  24  24  24  24  24  24  24   0  24   0  24  24  24  24  24  24  24  24  24  24  24  24  82  96   9
T |  96   0   6   6  24  24  24  24  24  24  24  24  24  24  24  96  24  96  24  24  24  24  24  24  24  24  24  24  24  24   0   0   6

scan!

home
updated Sat Dec 16 07:14:46 2023