5xn1_CD : 3D-footprint complex

structure name	HIV-1 REVERSE TRANSCRIPTASE Q151M:DNA:ENTECAVIR-TRIPHOSPHATE TERNARY COMPLEX
reference	Yasutake et al. 'Sci 8 1624 2018
source	HUMAN IMMUNODEFICIENCY VIRUS 1
experiment	X-ray (resolution=2.45, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	6kdn_B 7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5xn1_C interface=22,59,61,72,74,76,92,113,181,182,263,446,473,499, spietvpvklkpgmdgpkvkqWplteekikalveictemekegkiskigpenpyntpvFaIkkkdstkwrkLvDfRelnkrtqdfwevqlgIphpaglkqkksvtvldvgdaYfsvpldkdfrkytaftipsinnetpgiryqynvlpmgwkgspaifqssmtkilepfrkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwgfttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklNwasqiyagikvrqlskllrgtkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwyqlekepiigaetfyvdgaanRetklgkagyvtdrgrqkvvpltdttnQktelqaihlalqdsglevnivtdsqYalgiiqaqpdkseselvsqiieqlikkekvylawvpahkgiggneqvdklvs > 5xn1_D interface= pietvpvklkpgmdgpkvkqwPlteekikalveictemekegkiskigpenpyntpvfAiKkkdstkwrklVdFrElnkrtqdfwevqlgiPhpaglkqkksvtvldvgdayFsvpldkdfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqyMDdlyvgsdleigqhrtkieelrqhllrwggyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiyagikvrqlsklLrgtkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwy
interface signature	WFILDRIYYMNRQY/PAKVFEPFMDL

Estimated binding specificities ?

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# IC=9.613 IC/col=0.291 n_of_columns=33

specificity:

A |   0   0  15   0  24  24  24  24  24  24  24  24  24  24  24   3  24   3  10  24  24  24  24  24  24  24  24  24  24  24   3   0  13
C |   0  96  11  96  24  24  24  24  24  24  24  24  24  24  24   3  24   3   7  24  24  24  24  24  24  24  24  24  24  24   3   0  61
G |   0   0  61   0  24  24  24  24  24  24  24  24  24  24  24   3  24   3  76  24  24  24  24  24  24  24  24  24  24  24  90  96  11
T |  96   0   9   0  24  24  24  24  24  24  24  24  24  24  24  87  24  87   3  24  24  24  24  24  24  24  24  24  24  24   0   0  11

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updated Sat Dec 16 07:14:18 2023