5txo_CD : 3D-footprint complex

structure name	STRUCTURE OF Q151M COMPLEX (A62V, V75I, F77L, F116Y, Q151M) MUTANT HIV-1 REVERSE TRANSCRIPTASE (RT) TERNARY COMPLEX WITH A DOUBLE STRANDED DNA AND AN INCOMING DATP
reference	Martinez et al.
experiment	X-ray (resolution=2.55, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	7ozw_A 7ozw_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5txo_C interface=96,117,159,185,186,358,450, mvpispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfvikkkdstkwrklidlrelnkrtqdfwevqlgIphpaglkkkksvtvldvgdaYysvpldedfrkytaftipsinnetpgiryqynvlpmgwkgsPaifqssmtkilepfkkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndicklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyaRmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepivgaetfyvdgaanRetklgkagyvtnkgrqkvvpltnttnqktelqaiylalqdsglevnivtnsqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahkgiggneqvdklvsa > 5txo_D interface= pietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaGlkkkksvtvldvgdayfsvpLdedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqSsmtkilepfkkqnpdiviyqymddlYVgsdleigqhrtkieelrqhllrwglttpgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqKittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyq
interface signature	IYPYMRR/GLSYVK

Estimated binding specificities ?

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# IC=3.835 IC/col=0.226 n_of_columns=17

specificity:

A |   7   0   7  24  24  24  24  24  24  24  24  24  24  24  24  73  22
C |   7   0  81  24  24  24  24  24  24  24  24  24  24  24  24   7  66
G |  75  96   7  24  24  24  24  24  24  24  24  24  24  24  24   7   7
T |   7   0   1  24  24  24  24  24  24  24  24  24  24  24  24   9   1

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updated Sat Dec 16 05:51:38 2023