5txo_AB : 3D-footprint complex

structure name	STRUCTURE OF Q151M COMPLEX (A62V, V75I, F77L, F116Y, Q151M) MUTANT HIV-1 REVERSE TRANSCRIPTASE (RT) TERNARY COMPLEX WITH A DOUBLE STRANDED DNA AND AN INCOMING DATP
reference	Martinez et al.
experiment	X-ray (resolution=2.55, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	7ozw_A 7ozw_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5txo_A interface=96,117,159,185,186,358,450,477, mvpispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfvikkkdstkwrklidlrelnkrtqdfwevqlgIphpaglkkkksvtvldvgdaYysvpldedfrkytaftipsinnetpgiryqynvlpmgwkgsPaifqssmtkilepfkkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndicklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyaRmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepivgaetfyvdgaanRetklgkagyvtnkgrqkvvpltnttnQktelqaiylalqdsglevnivtnsqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahkgiggneqvdklvsa > 5txo_B interface= pietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaGlkkkksvtvldvgdayfsvpLdedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqSsmtkilepfkkqnpdiviyqymddlYVgsdleigqhrtkieelrqhllrwglttpgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqKittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyq
interface signature	IYPYMRRQ/GLSYVK

Estimated binding specificities ?

contact

# IC=3.627 IC/col=0.213 n_of_columns=17

specificity:

A |   7   7  24  24  24  24  24  24  24  24  24  24  24  24   7   0   7
C |   9   7  24  24  24  24  24  24  24  24  24  24  24  24  75  96   7
G |  73   9  24  24  24  24  24  24  24  24  24  24  24  24   7   0  73
T |   7  73  24  24  24  24  24  24  24  24  24  24  24  24   7   0   9

scan!

home
updated Sat Dec 16 05:52:10 2023