5txn_CD : 3D-footprint complex

structure name	STRUCTURE OF Q151M MUTANT HIV-1 REVERSE TRANSCRIPTASE (RT) TERNARY COMPLEX WITH A DOUBLE STRANDED DNA AND AN INCOMING DATP
reference	Martinez et al.
experiment	X-ray (resolution=2.55, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	7ozw_A 7ozw_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5txn_C interface=95,116,158,184,185,357,449, vpispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgIphpaglkkkksvtvldvgdaYfsvpldedfrkytaftipsinnetpgiryqynvlpmgwkgsPaifqssmtkilepfkkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndicklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyaRmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepivgaetfyvdgaanRetklgkagyvtnkgrqkvvpltnttnqktelqaiylalqdsglevnivtnsqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahkgiggneqvdklvsa > 5txn_D interface= pietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgiphpAglkkkksvtvldvgdayfsvPldedfrkytaftipsinnetpgiryqynvlpqgwkgspaifQssmtkilepfkkqnpdiviyqymddLYvgsdleigqhrtkieelrqhllrwglttpgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavQkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyq
interface signature	IYPYMRR/APQLYQ

Estimated binding specificities ?

contact

# IC=2.850 IC/col=0.178 n_of_columns=16

specificity:

A |   9   0  21  24  24  24  24  24  24  24  24  24  24  24  24  78
C |   9   0  57  24  24  24  24  24  24  24  24  24  24  24  24   9
G |  69  96   9  24  24  24  24  24  24  24  24  24  24  24  24   9
T |   9   0   9  24  24  24  24  24  24  24  24  24  24  24  24   0

scan!

home
updated Sat Dec 16 05:50:34 2023