structure nameHUMAN HOLO-PIC IN THE INITIAL TRANSCRIBING STATE
sourceHOMO SAPIENS
experimentNMR
structural superfamilyCyclin-like;Zinc beta-ribbon;Transcription factor IIA TFIIA, beta-barrel domain;Transcription factor IIA TFIIA, alpha-helical domain;TATA-box binding protein-like;Rap30/74 interaction domains;"Winged helix" DNA-binding domain;P-loop containing nucleoside triphosphate hydrolases;
reference complex5iy6_M 5iy6_N 5iy6_P 5iy6_T 5iy6_V
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureMKTR/WYKYKKQIKR//RFSNASNKNRTRNK/EEPLEEFHLGRKDW/NVFLFVTNFPLFVT/KIH/L

Estimated binding specificities ?

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# IC=35.753 IC/col=0.586 n_of_columns=61 specificity:   
A |   1   5  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   9   0   0  24   1  96   1   0   4  96   0  24  96   8   9  96  96   0   0   0   3   0   0  24  24  24  24  24  24  24  24   0   0   0   0   0  96   0  82
C |   4   8  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   9  96   0  24   4   0  90   0   1   0   0  24   0  76  11   0   0  96   0  96   6  96  96  24  24  24  24  24  24  24  24  96   0   9  96   0   0   0   5
G |  90   7  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  11   0  96  24  90   0   4   0  90   0  96  24   0   5  69   0   0   0  96   0  84   0   0  24  24  24  24  24  24  24  24   0   0   1   0   0   0   0   4
T |   1  76  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  67   0   0  24   1   0   1  96   1   0   0  24   0   7   7   0   0   0   0   0   3   0   0  24  24  24  24  24  24  24  24   0  96  86   0  96   0  96   5
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updated Sat Dec 16 02:27:09 2023