interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA INSERTING DGMPNPP OPPOSITE O4-METHYLHYMIDINE
(DNA polymerase eta)
referenceOFlaherty et al. 'Chem 7 4896 2016
sourceHomo sapiens
experimentX-ray (resolution=2.35, R-factor=0.175)
structural superfamilyDNA/RNA polymerases;Lesion bypass DNA polymerase Y-family, little finger domain;
sequence familyimpB/mucB/samB family;
reference complex3jaa_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRSR

Estimated binding specificities ?

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# IC=1.372 IC/col=0.229 n_of_columns=6 specificity:   
A |  60  19  24  24  13   4
C |  12  19  24  24  56   4
G |  12  20  24  24  13  81
T |  12  38  24  24  14   7
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updated Mon Dec 18 12:30:47 2023