interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE PROTOTYPE FOAMY VIRUS INTASOME WITH A 2- PYRIDINONE AMINAL INHIBITOR
(INTEGRASE)
referenceKlein et al. J.Med.Chem. 58 8154 2015
sourceHUMAN SPUMARETROVIRUS
experimentX-ray (resolution=2.70, R-factor=0.192)
structural superfamilyRibonuclease H-like;
sequence familyIntegrase core domain;
reference complex3oym_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureIRQERP

Estimated binding specificities ?

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# IC=2.294 IC/col=0.573 n_of_columns=4 specificity:   
A |   2   6  13  45
C |   1   6  63  16
G |  92   6  10  16
T |   1  78  10  19
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updated Mon Dec 18 11:47:41 2023