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structure nameCRYSTAL STRUCTURE OF THE MOT1 N-TERMINAL DOMAIN IN COMPLEX WITH TBP AND NC2 BOUND TO A PROMOTER DNA FRAGMENT
(ECU04_1440 PROTEIN)
referenceA.BUTRYN et al. ELIFE V. 4 2015
sourceENCEPHALITOZOON CUNICULI (STRAIN GB-M1) / ENCEPHALITOZOON CUNICULI (STRAIN GB-M1)
experimentX-ray (resolution=3.78, R-factor=?)
structural superfamilyTATA-box binding protein-like;
sequence familyTranscription factor TFIID or TATAbinding;
multimeric complexes4wzs_ABD
links to other resourcesPDBSum NPIDB BIPA PDIdb DNAproDB
protein sequence
interface signatureNVFLFVTNVFPLFVT

Estimated binding specificities ?

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# IC=8.957 IC/col=0.995 n_of_columns=9 specificity:   
A |   7   0   9   0   0  73   0  96   7
C |  75   0   7   0   0   7   0   0   9
G |   7   0   7   0   0   7   0   0  73
T |   7  96  73  96  96   9  96   0   7
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: TBP
TATAAAAGPubMed4wzs_D(1.10e-13), 4wzs_ABD(1.10e-13)
TATAAAPubMed4wzs_D(1.19e-08), 4wzs_ABD(1.19e-08)
TGTAAAPubMed4wzs_D(3.30e-04), 4wzs_ABD(3.30e-04)
GGGTATAAAAGGPubMed4wzs_D(3.35e-10), 4wzs_ABD(3.37e-10)
AATAAAAGPubMed4wzs_D(2.06e-09), 4wzs_ABD(2.06e-09)
CATAAAPubMed4wzs_D(3.91e-05), 4wzs_ABD(3.91e-05)
CTTTTPubMed4wzs_D(3.62e-06), 4wzs_ABD(3.63e-06)
TAAAAAPubMed4wzs_D(3.91e-05), 4wzs_ABD(3.91e-05)
TATATAPubMed4wzs_D(3.30e-04), 4wzs_ABD(3.30e-04)
TATAAPubMed4wzs_D(3.62e-06), 4wzs_ABD(3.62e-06)
TATTTAAAPubMed4wzs_D(6.57e-03), 4wzs_ABD(6.57e-03)
TATATAAPubMed4wzs_D(6.03e-06), 4wzs_ABD(6.03e-06)
sitesourcematches (E-value)

Dendrogram of similar interfaces ?

matrix format
  
  NTVAFALAFTVGTTQGNTVAFAPALAFTVATT--   L            +----------------6cnc_R    
                                                    ! 
  NTVAFGLTFAVA----NAVTFAPALTFTVATA--   L   +--------4                +5iyd_P    
                                           !        !      +---------2 
  NTVAFCLTFAVATT--NAVTFTPALTFTVATA--   L   !        !      !         ! +4wzs_D    
                                           !        +------3         +-1 
  NTVAFTLTFAVATT--NAVTFAPALAFTVATA--   L --5               !           +1vto_B    
                                           !               ! 
  NTVTFALAFTVATT--NAVTFTPALTFAVTTA--   L   !               +---------4roc_B    
                                           ! 
  --------------------------------RT       +-------------------------6mup_M    
                                         

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updated Wed Jul 7 21:12:02 2021