4ond_EF : 3D-footprint complex

structure name	ANCESTRAL STEROID RECEPTOR 2 DBD HELIX MUTANT - ERE DNA COMPLEX
reference	Ortlund et al. 'Cell(Cambridge,Mass.)' 159 58 2014
source	synthetic construct
experiment	X-ray (resolution=2.25, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	5cbz_E
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4ond_E interface=22,25,26,30, qkvclicgdeasgchygvltcEgcKAffkRavegqhnylcagrndciidkirrkncpacrlrkclqagmtl > 4ond_F interface=22,25,26,30, qkvclicgdeasgchygvltcEgcKAffkRavegqhnylcagrndciidkirrkncpacrlrkclqagmtl
interface signature	EKAR/EKAR

Estimated binding specificities ?

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# IC=11.117 IC/col=0.794 n_of_columns=14

specificity:

A |   0   0   2  14  96  24  24  24   0  16  73   0   0   0
C |   2   0   0  45   0  24  24  24   0  14  19  96  96   2
G |  93  96   1  19   0  24  24  24   0  47   2   0   0   2
T |   1   0  93  18   0  24  24  24  96  19   2   0   0  92

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updated Fri Dec 15 20:22:16 2023