interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF RUNX1 AND ETS1 BOUND TO TCR ALPHA PROMOTER (CRYSTAL FORM 1)
(RUNT-RELATED TRANSCRIPTION FACTOR 1)
referenceLeukemia 28 2040 2014
sourceMUS MUSCULUS
experimentX-ray (resolution=2.50, R-factor=0.225)
structural superfamilyp53-like transcription factors;
sequence familyRunt domain;
multimeric complexes4l0y_AB 4l0z_AB
redundant complexes4l0z
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRVDRR

Estimated binding specificities ?

readout + contactlogo
# IC=7.286 IC/col=0.911 n_of_columns=8 specificity:   
A |   0   0  12   0   0   0   6   6
C |   6   0   6   0   0  30  12   6
G |   6  96   6  96  96   0  12   6
T |  84   0  72   0   0  66  66  78
scan!

Dendrogram of similar interfaces ?

matrix format
  
  RGRTVCDC--RG   L                                +4l0y_A    
                                                +-1 
  RGRTVCDC--RG   L                            +-2 +4l18_E    
                                              ! ! 
  RGRTVCDC--RG   L        +-------------------3 +3wu1_A    
                          !                   ! 
  RGRAVCDC--RT   L      +-4                   +-6vg8_D    
                        ! ! 
  ----------RG       +--5 +---------------------7b4n_A    
                     !  ! 
  ----ATCT--RG     --6  +-----------------------3qyn_C    
                     ! 
  ----VTHGNTQT   L   +--------------------------4y5w_B

home
updated Tue Dec 19 09:03:55 2023