interface graph thumbnail
legend  pdf

structure nameHUMAN DNA POLYMERASE ETA-DNA TERNARY COMPLEX: MISINCORPORATION G OPPOSITE T AFTER A T AT THE PRIMER 3' END (TA/G)
(DNA polymerase eta)
referenceBiertumpfel et al. Proc.Natl.Acad.Sci.USA 110 8146 2013
sourceHomo sapiens
experimentX-ray (resolution=2.03, R-factor=0.165)
structural superfamilyDNA/RNA polymerases;Lesion bypass DNA polymerase Y-family, little finger domain;
sequence familyimpB/mucB/samB family;
reference complex3jaa_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRSNLRMF

Estimated binding specificities ?

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# IC=3.900 IC/col=0.650 n_of_columns=6 specificity:   
A |  96   4  21  24  13   0
C |   0   4  21  24  63   0
G |   0   4  33  24  10  96
T |   0  84  21  24  10   0
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updated Mon Dec 18 10:39:30 2023