4g0v_AB : 3D-footprint complex

structure name	HUMAN TOPOISOMERASE IIBETA IN COMPLEX WITH DNA AND MITOXANTRONE
reference	Chan et al. 'Nucleic 41 10630 2013
source	Homo sapiens
experiment	X-ray (resolution=2.55, R-factor=?)
structural superfamily	Type II DNA topoisomerase;
reference complex	3qx3_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4g0v_A interface=52,54,211,214,215,263,264,357,362,364, kgipklddandaggkhslectliltegdsakslavsglgvigrdrygvfplRgKilnvreashkqimenaeinniikivglqykksyddaeslktlrygkimimtdqdqdgshikgllinfihhnwpsllkhgfleefitdmerhrilfryagpeddaaitlafskkkiddrkewltnfmedrrqrrlhglkhltyndfinkelilfsnsDneRSipslvdgfkpgqrkvlftcfkrndkrevkvaqlagsvaemsayhhgeQAlmmtivnlaqnfvgsnninllqpigqfgtrlhggkdaaspryiftmlstlarllfpavddnllkflyddnqrvepewyipiipmvlingaegIgtgwAcKlpnydareivnnvrrmldgldphpmlpnyknfkgtiqelgqnqyavsgeifvvdrntveitelpvrtwtqvykeqvlepmlngtdktpalisdykeyhtdttvkfvvkmteeklaqaeaaglhkvfklqttltcnsmvlfdhmgclkkyetvqdilkeffdlrlsyyglrkewlvgmlgaestklnnqarfilekiqgkitienrskkdliqmlvqrgyesdpvkawkeaqegpdfnyilnmslwsltkekveelikqrdakgrevndlkrkspsdlwkedlaafveeldkvesqered > 4g0v_B interface=55,57,219,222,223,271,272,275,313,365,370, skikgipklddandaggkhslectliltegdsakslavsglgvigrdrygvfplRgKilnvreashkqimenaeinniikivglqykksyddaeslktlrygkimimtdqdqdgshikgllinfihhnwpsllkhgfleefiakeakeyfadmerhrilfryagpeddaaitlafskkkiddrkewltnfmedrrqrrlkhltyndfinkelilfsnsDneRSipslvdgfkpgqrkvlftcfkrndkrevkvaqlagsvaemsayhhgeQAlmMtivnlaqnfvgsnninllqpigqfgtrlhggkdaaspRyiftmlstlarllfpavddnllkflyddnqrvepewyipiipmvlingaegIgtgwAcklpnydareivnnvrrmldgldphpmlpnyknfkgtiqelgqnqyavsgeifvvdrntveitelpvrtwtqvykeqvlepmlngpalisdykeyhtdttvkfvvkmteeklaqaeaaglhkvfklqttltcnsmvlfdhmgclkkyetvqdilkeffdlrlsyyglrkewlvgmlgaestklnnqarfilekiqgkitienrskkdliqmlvqrgyesdpvkawkeaqgpdfnyilnmslwsltkekveelikqrdakgrevndlkrkspsdlwkedlaafveeldkvesqered
interface signature	RKDRSQAIAK/RKDRSQAMRIA

Estimated binding specificities ?

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# IC=14.312 IC/col=1.022 n_of_columns=14

specificity:

A |   0   0  12   0   3   0   9   0  96  12   0  90   0   0
C |  96   0  12   0  75   0   6  87   0   6  90   6  96   0
G |   0  96  57  96   6   0  66   0   0  66   3   0   0  96
T |   0   0  15   0  12  96  15   9   0  12   3   0   0   0

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updated Fri Dec 15 18:56:20 2023