4g0u_AB : 3D-footprint complex

structure name	HUMAN TOPOISOMERASE IIBETA IN COMPLEX WITH DNA AND AMSACRINE
reference	Chan et al. 'Nucleic 41 10630 2013
source	Homo sapiens
experiment	X-ray (resolution=2.70, R-factor=?)
structural superfamily	Type II DNA topoisomerase;
reference complex	3qx3_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4g0u_A interface=49,51,203,206,255,256,297,347,349,354, pklddandaggkhslectliltegdsakslavsglgvigrdrygvfplRgKilnvreashkqimenaeinniikivglqykksyddaeslktlrygkimimtdqdqdgshikgllinfihhnwpsllkhgfleefiterhrilfryagpeddaaitlafskkkiddrkewltnfmedrrqrrlkhltyndfinkelilfsnsDneRsipslvdgfkpgqrkvlftcfkrndkrevkvaqlagsvaemsayhhgeQAlmmtivnlaqnfvgsnninllqpigqfgtrlhggkdaaspRyiftmlstlarllfpavddnllkflyddnqrvepewyipiipmvlingaEgIgtgwAcklpnydareivnnvrrmldgldphpmlpnyknfkgtiqelgqnqyavsgeifvvdrntveitelpvrtwtqvykeqvlepmlngtdktpalisdykeyhtdttvkfvvkmteeklaqaeaaglhkvfklqttltcnsmvlfdhmgclkkyetvqdilkeffdlrlsyyglrkewlvgmlgaestklnnqarfilekiqgkitienrskkdliqmlvqrgyesdpvkawkeaqegpdfnyilnmslwsltkekveelikqrdakgrevndlkrkspsdlwkedlaafveeldkvesqered > 4g0u_B interface=51,53,217,220,221,269,270,311,361,363,368,370, gipklddandaggkhslectliltegdsakslavsglgvigrdrygvfplRgKilnvreashkqimenaeinniikivglqykksyddaeslktlrygkimimtdqdqdgshikgllinfihhnwpsllkhgfleefitakeakeyfadmerhrilfryagpeddaaitlafskkkiddrkewltnfmedrrqrrltkhltyndfinkelilfsnsDneRSipslvdgfkpgqrkvlftcfkrndkrevkvaqlagsvaemsayhhgeQAlmmtivnlaqnfvgsnninllqpigqfgtrlhggkdaaspRyiftmlstlarllfpavddnllkflyddnqrvepewyipiipmvlingaEgIgtgwAcKlpnydareivnnvrrmldgldphpmlpnyknfkgtiqelgqnqyavsgeifvvdrntveitelpvrtwtqvykeqvlepmlngtdktpalisdykeyhtdttvkfvvkmteeklaqaeaaglhkvfklqttltcnsmvlfdhmgclkkyetvqdilkeffdlrlsyyglrkewlvgmlgaestklnnqarfilekiqgkitienrskkdliqmlvqrgyesdpvkawkeaqgpdfnyilnmslwsltkekveelikqrdakgrevndlkrkspsdlwkedlaafveeldkvesqered
interface signature	RKDRQAREIA/RKDRSQAREIAK

Estimated binding specificities ?

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# IC=12.461 IC/col=0.890 n_of_columns=14

specificity:

A |   0   0  24   4   4   0   4   4  96   4   4  24   0   0
C |  96   0  24   4  76   0   4  84   0   4  81  24  96   0
G |   0  96  24  81   7   0  81   4   0  76   7  24   0  96
T |   0   0  24   7   9  96   7   4   0  12   4  24   0   0

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updated Fri Dec 15 18:55:29 2023