4b3q_AB : 3D-footprint complex

structure name	STRUCTURES OF HIV-1 RT AND RNA-DNA COMPLEX REVEAL A UNIQUE RT CONFORMATION AND SUBSTRATE INTERFACE
reference	Le Grice et al. Nat.Struct.Mol.Biol. 20 230 2013
source	HUMAN IMMUNODEFICIENCY VIRUS 1
experiment	X-ray (resolution=5.00, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	4b3p_B 7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4b3q_A interface=217,252,253,345,462,488, pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfvdfrelnkktqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwMgyelhpdkwtvqpivlpekdswtvndiqklvgklNWasqiypgikvrqlckllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmRgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwvpewefvntpplvklwyqlekepivgaetfyvdgaasretklgkagyvtnkgrqkvvtltdttnQktelqaihlalqdsglevnivtnsqYalgiiqaqpdqseselvnqiieqlikkekvylawvpahkgiggneqvdklvsagi > 4b3q_B interface=397, tvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdgtkwrklvdfrelnkktqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymddlyvgsdleigqhrtkieelrqhllrwgltgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwvpewefvNtpplvklwyqlek
interface signature	MNWRQY/N

Estimated binding specificities ?

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# IC=3.415 IC/col=0.244 n_of_columns=14

specificity:

A |   6  24  24   6  24  24   6  24  24  24  24  24   6   6
C |  78  24  24   6  24  24   6  24  24  24  24  24   6   6
G |   6  24  24   6  24  24   6  24  24  24  24  24   6  78
T |   6  24  24  78  24  24  78  24  24  24  24  24  78   6

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updated Fri Dec 15 18:35:44 2023