interface graph thumbnail
legend  pdf

structure nameTHE OESTROGEN RECEPTOR RECOGNIZES AN IMPERFECTLY PALINDROMIC RESPONSE ELEMENT THROUGH AN ALTERNATIVE SIDE-CHAIN CONFORMATION
(ESTROGEN RECEPTOR)
referenceSchwabe et al. Structure 3 201 1995
sourceHOMO SAPIENS
experimentX-ray (resolution=2.60, R-factor=0.222)
structural superfamilyGlucocorticoid receptor-like DNA-binding domain;
sequence familyZinc finger, C4 type two domains;
multimeric complexes1hcq_AB 1hcq_EF 4aa6_AB 4aa6_EF
reference complex1hcq_E
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureEKAKR

Estimated binding specificities ?

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# IC=5.582 IC/col=0.930 n_of_columns=6 specificity:   
A |  60  60   0   0   0  96
C |  12  12   0   0  84   0
G |  12  12  96   0   0   0
T |  12  12   0  96  12   0
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updated Mon Dec 18 09:44:27 2023