3ts8_ABCD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A MULTIDOMAIN HUMAN P53 TETRAMER BOUND TO THE NATURAL CDKN1A(P21) P53-RESPONSE ELEMENT
reference	Halazonetis et al. 'Mol 9 1493 2011
source	HOMO SAPIENS
experiment	X-ray (resolution=2.80, R-factor=?)
structural superfamily	p53-like transcription factors;p53 tetramerization domain;
reference complex	3q05_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3ts8_A interface=155,183,184,187, sssvpsqktyqgsygfrlgflhsgtaksvtctyspalnkmfvqlaktvpvqlyvdstpppgtrvramaiykqsqhmtevvrrcphherssdsdglappqhlirvegnlraeylddpntfrhsvvvpyeppevgsdyttiyfkfmcnsscmggmnRrpilviitledssgnllgrdsfevrvcACpgRdrrteeenlrkktmdgeyftlqirgrerfeqfrernealelkdaqat > 3ts8_B interface=27,155,183,184,187, sssvpsqktyqgsygfrlgflhsgtaKsvtctyspalnkmfvqlaktvpvqlyvdstpppgtrvramaiykqsqhmtevvrrcphherssdsdglappqhlirvegnlraeylddpntfrhsvvvpyeppevgsdyttiyfkfmcnsscmggmnRrpilviitledssgnllgrdsfevrvcACpgRdrrteeenlrkktmdgeyftlqirgrerfeqfrernealelkdaqat > 3ts8_C interface=27,183,184,187, sssvpsqktyqgsygfrlgflhsgtaKsvtctyspalnkmfvqlaktvpvqlyvdstpppgtrvramaiykqsqhmtevvrrcphherssdsdglappqhlirvegnlraeylddpntfrhsvvvpyeppevgsdyttiyfkfmcnsscmggmnrrpilviitledssgnllgrdsfevrvcACpgRdrrteeenlrkktmdgeyftlqirgrerfeqfrernealelkdaqat > 3ts8_D interface=155,183,184,187, sssvpsqktyqgsygfrlgflhsgtaksvtctyspalnkmfvqlaktvpvqlyvdstpppgtrvramaiykqsqhmtevvrrcphherssdsdglappqhlirvegnlraeylddpntfrhsvvvpyeppevgsdyttiyfkfmcnsscmggmnRrpilviitledssgnllgrdsfevrvcACpgRdrrteeenlrkktmdgeyftlqirgrerfeqfrernealelkdaqat
interface signature	RACR/KRACR/KACR/RACR

Estimated binding specificities ?

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# IC=11.429 IC/col=0.816 n_of_columns=14

specificity:

A |   0  81   0   0  24  11  24   4   2  72   0  88   1   0
C |  96   2   0   0  24  56  24  16   2  11  96   6   2   0
G |   0  11   0  85  24   2  24  65  18  11   0   2   0  96
T |   0   2  96  11  24  27  24  11  74   2   0   0  93   0

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updated Fri Dec 15 17:01:45 2023