interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE PROTOTYPE FOAMY VIRUS (PFV) INTASOME IN COMPLEX WITH MAGNESIUM AND DOLUTEGRAVIR (S/GSK1349572)
(PFV INTEGRASE)
referenceCherepanov et al. Mol.Pharmacol. 80 565 2011
sourceHUMAN SPUMARETROVIRUS
experimentX-ray (resolution=2.49, R-factor=0.207)
structural superfamilyRibonuclease H-like;
sequence familyIntegrase core domain;
reference complex3oym_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureIRQERSP

Estimated binding specificities ?

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# IC=2.178 IC/col=0.545 n_of_columns=4 specificity:   
A |  16   8  81   6
C |  16   7   4  78
G |  16  74   4   6
T |  48   7   7   6
scan!

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updated Mon Dec 18 09:06:44 2023