interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE PFV S217H MUTANT INTASOME BOUND TO MANGANESE
(PFV integrase)
referenceCherepanov et al. Proc.Natl.Acad.Sci.USA 107 20057 2010
sourceHuman spumaretrovirus
experimentX-ray (resolution=2.72, R-factor=0.203)
structural superfamilyRibonuclease H-like;
sequence familyIntegrase core domain;
reference complex3oym_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureIRQERSP

Estimated binding specificities ?

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# IC=1.900 IC/col=0.475 n_of_columns=4 specificity:   
A |  19   9  74   4
C |  16   9   8  81
G |  16  67   7   7
T |  45  11   7   4
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updated Mon Dec 18 08:43:09 2023