interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF DEST IN COMPLEX WITH DUPLEX DNA
(DEST)
referenceMiller et al. Nat.Struct.Mol.Biol. 17 971 2010
sourcePSEUDOMONAS AERUGINOSA
experimentX-ray (resolution=2.55, R-factor=0.229)
structural superfamilyHomeodomain-like;
sequence familyBacterial regulatory proteins, tetR family;
redundant complexes3lsp_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureLRPAY

Estimated binding specificities ?

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# IC=4.471 IC/col=1.118 n_of_columns=4 specificity:   
A |   0   0   0   9
C |  96   0   0   9
G |   0  96   0   9
T |   0   0  96  69
scan!

Dendrogram of similar interfaces ?

matrix format
  
  LTRG--PTAC--YT--   L                              +-3lsr_A    
                                     +--------------1 
  VT--AGDT--TTYTLA   L         +-----2              +-5gpc_B    
                               !     ! 
  ----TTRG----YTWA   L       +-3     +----------------7jnp_A    
                             ! ! 
  ----STVTAGTTFANT   L     +-4 +----------------------7amn_A    
                           ! ! 
  LC--RTPTPTSTYT--   L   +-5 +-----------------------6nsn_B    
                         ! ! 
  ----TGKG----YCFA   L --6 +-------------------------4pxi_B    
                         ! 
  MTRGTGPT--ATYTWT   L   +--------------------------5yej_B    
                       

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updated Tue Dec 19 07:49:08 2023