3kmd_ABCD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE P53 CORE DOMAIN BOUND TO A FULL CONSENSUS SITE AS A SELF-ASSEMBLED TETRAMER
reference	Chen et al. Structure 18 246 2010
source	HOMO SAPIENS
experiment	X-ray (resolution=2.15, R-factor=?)
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3kmd_A interface=185,186,189, plsssvpsqktyqgsygfrlgflhsgtaksvtctyspalnkmfcqlaktcpvqlwvdstpppgtrvramaiykqsqhmtevvrrcphhercsdsdglappqhlirvegnlrveylddrntfrhsvvvpyeppevgsdcttihynymcnsscmggmnrrpiltiitledssgnllgrnsfevrvcACpgRdrrteeenlrk > 3kmd_B interface=29,30,185,186,189, plsssvpsqktyqgsygfrlgflhsgtaKSvtctyspalnkmfcqlaktcpvqlwvdstpppgtrvramaiykqsqhmtevvrrcphhercsdsdglappqhlirvegnlrveylddrntfrhsvvvpyeppevgsdcttihynymcnsscmggmnrrpiltiitledssgnllgrnsfevrvcACpgRdrrteeenlrk > 3kmd_C interface=29,157,185,186,189, plsssvpsqktyqgsygfrlgflhsgtaKsvtctyspalnkmfcqlaktcpvqlwvdstpppgtrvramaiykqsqhmtevvrrcphhercsdsdglappqhlirvegnlrveylddrntfrhsvvvpyeppevgsdcttihynymcnsscmggmnRrpiltiitledssgnllgrnsfevrvcACpgRdrrteeenlrk > 3kmd_D interface=29,30,157,185,186,189, plsssvpsqktyqgsygfrlgflhsgtaKSvtctyspalnkmfcqlaktcpvqlwvdstpppgtrvramaiykqsqhmtevvrrcphhercsdsdglappqhlirvegnlrveylddrntfrhsvvvpyeppevgsdcttihynymcnsscmggmnRrpiltiitledssgnllgrnsfevrvcACpgRdrrteeenlrk
interface signature	ACR/KSACR/KRACR/KSRACR

Estimated binding specificities ?

readout + contact

# IC=18.592 IC/col=1.094 n_of_columns=17

specificity:

A |   9  24   0  76   0   0   0   0   0  96   0   0   0  96   0   0   9
C |  11  24  96  11   0   0  96  96   0   0   0   0  96   0   9   0  69
G |  67  24   0   9   0  96   0   0   0   0  96  96   0   0   1  96   9
T |   9  24   0   0  96   0   0   0  96   0   0   0   0   0  86   0   9

scan!

home
updated Fri Dec 15 15:20:31 2023