3klh_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF AZT-RESISTANT HIV-1 REVERSE TRANSCRIPTASE CROSSLINKED TO POST-TRANSLOCATION AZTMP-TERMINATED DNA (COMPLEX P)
reference	Sarafianos et al. Nat.Struct.Mol.Biol. 17 1202 2010
source	HUMAN IMMUNODEFICIENCY VIRUS TYPE 1
experiment	X-ray (resolution=2.90, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	3klh_B 7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3klh_A interface=94,157,183,184,265,356,358,448, pispietvpvklkpgmdgpkvkqwplteekikalveictelekegkiskigpenpyntpvfaikkknstrwrklvdfrelnkrtqdfwevqlgIphpaglkkkksvtvldvgdayfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgsPaifqssmtkilepfkkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwglytpdqkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndicklvgklNwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyaRmRgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepivgaetfyvdgaanRetklgkagyvtnkgrqkvvpltnttnqktelqaiylalqdsglevnivtdsqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahkgiggneqvdklvsagirk > 3klh_B interface= pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgIphpaglkkkksvtvldvgdayfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgsPaifqssmtkilepfkkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklNwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyaRmRgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyq
interface signature	IPYMNRRR/IPYMNRR

Estimated binding specificities ?

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# IC=3.976 IC/col=0.234 n_of_columns=17

specificity:

A |   0   1  24  24  24  24  24  24  24  24  24  24  24  24   7  73   7
C |   0   0  24  24  24  24  24  24  24  24  24  24  24  24  14   9  81
G |  96  88  24  24  24  24  24  24  24  24  24  24  24  24  51   7   8
T |   0   7  24  24  24  24  24  24  24  24  24  24  24  24  24   7   0

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updated Fri Dec 15 15:19:55 2023