3hxq_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF VON WILLEBRAND FACTOR (VWF) A1 DOMAIN IN COMPLEX WITH DNA APTAMER ARC1172, AN INHIBITOR OF VWF-PLATELET BINDING (von Willebrand Factor)
reference	Fremont et al.
source	Homo sapiens
experiment	X-ray (resolution=2.69, R-factor=0.223)
structural superfamily	vWA-like;
sequence family	von Willebrand factor type A domain;
reference complex	3hxo_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3hxq_A interface=23,102,124,126,127,128,130,131,132,133,157,158,159,163, pplhdfycsrlldlvflldgssRlseaefevlkafvvdmmerlrisqkwvrvavveyhdgshayiglkdrkrpselrriasqvkyagsqvastsevlkytlFqifskidrpeasrialllmasQePQRmSRNFvryvqglkkkkvivipvgigphaNLKqirLiekqapenkafvlssvdeleqqrdeivsylcdlapeap
interface signature	RFQPQRSRNFNLKL

Estimated binding specificities ?

readout + contact

# IC=16.180 IC/col=0.622 n_of_columns=26

specificity:

A |  14  96  24   0  24  24  24  24  24  24  24  24  24  24  24   0  24   0   0   0   0   0   0   0   0   0
C |  52   0  24   0  24  24  24  24  24  24  24  24  24  24  24   0  24  96   0   0   0   0  96  96   0  96
G |  14   0  24   0  24  24  24  24  24  24  24  24  24  24  24   0  24   0  96  96   0  96   0   0   0   0
T |  16   0  24  96  24  24  24  24  24  24  24  24  24  24  24  96  24   0   0   0  96   0   0   0  96   0

scan!

home
updated Mon Dec 18 08:06:15 2023