3e00_AD : 3D-footprint complex

structure name	INTACT PPAR GAMMA - RXR ALPHA NUCLEAR RECEPTOR COMPLEX ON DNA BOUND WITH GW9662, 9-CIS RETINOIC ACID AND NCOA2 PEPTIDE
reference	Rastinejad et al. Nature 456 350 2008
source	HOMO SAPIENS
experiment	X-ray (resolution=3.10, R-factor=?)
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3e00_A interface=22,25,29,30, khicaicgdrssgkhygvyscEgcKgffKRtvrkdltytcrdnkdclidkrqrnrcqycryqkclamgmkreavqeerqranedmpverileaelavevtnicqaadkqlftlvewakriphfselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagvgaifdrvltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyasleayckhkypeqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmeml > 3e00_D interface=23,26,30,31,34,76,78, maiecrvcgdkasgfhygvhacEgcKgffRRtiRlkliydrcdlncrihkksrnkcqycrfqkclavgmshnairFgRmpqaekekllaeissdidqlnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqvikktetdmslhpllqeiykdly
interface signature	EKKR/EKRRRFR

Estimated binding specificities ?

readout + contact

# IC=13.442 IC/col=0.747 n_of_columns=18

specificity:

A |   4   0  24   0   0  24  24   0   0  96   0   0   8  24  24   8   4   8
C |   4   0  24  96  96  24  24   0   0   0  96  96   4  24  24  20   8   4
G |   4  96  24   0   0  24  24   4  96   0   0   0   8  24  24  24  12   4
T |  84   0  24   0   0  24  24  92   0   0   0   0  76  24  24  44  72  80

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updated Fri Dec 15 14:22:00 2023