interface graph thumbnail
legend  pdf

structure nameINTACT PPAR GAMMA - RXR ALPHA NUCLEAR RECEPTOR COMPLEX ON DNA BOUND WITH BVT.13, 9-CIS RETINOIC ACID AND NCOA2 PEPTIDE
(PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA)
referenceRastinejad et al. Nature 456 350 2008
sourceHOMO SAPIENS
experimentX-ray (resolution=3.20, R-factor=?)
structural superfamilyNuclear receptor ligand-binding domain;Glucocorticoid receptor-like DNA-binding domain;
sequence familyZinc finger, C4 type two domains; Ligandbinding domain of nuclear hormon;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureEKRRR

Estimated binding specificities ?

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# IC=8.434 IC/col=0.767 n_of_columns=11 specificity:   
A |   3  15  96   0   0   3  24  24   3   0   7
C |   6  15   0  96  92   3  24  24   3   0  15
G |   3  53   0   0   3   6  24  24   3   0   9
T |  84  13   0   0   1  84  24  24  87  96  65
scan!

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updated Mon Dec 18 07:49:24 2023