3d0a_AC : 3D-footprint complex

structure name	HUMAN P53 CORE DOMAIN WITH HOT SPOT MUTATION R249S AND SECOND SITE SUPPRESSOR MUTATION H168R IN SEQUENCE-SPECIFIC COMPLEX WITH DNA
reference	Rozenberg et al. J.Mol.Biol. 385 249 2009
source	Homo sapiens
experiment	X-ray (resolution=1.80, R-factor=?)
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3d0a_A interface=25,26,28,41,44,180,181,184, svpsqktyqgsygfrlgflhsgtaKSvTctyspalnkmfcQlaKtcpvqlwvdstpppgtrvramaiykqsqrmtevvrrcphhercdsdglappqhlirvegnlrveylddrntfrhsvvvpyeppevgsdcttihynymcnsscmggmnrspiltiitledssgnllgrnsfevrvcACpgRdrrteeenlrk > 3d0a_C interface=25,181,182,185, svpsqktyqgsygfrlgflhsgtaKsvtctyspalnkmfcqlaktcpvqlwvdstpppgtrvramaiykqsqrmtevvrrcphhercsdsdglappqhlirvegnlrveylddrntfrhsvvvpyeppevgsdcttihynymcnsscmggmnrspiltiitledssgnllgrnsfevrvcACpgRdrrteeen
interface signature	KSTQKACR/KACR

Estimated binding specificities ?

readout + contact

# IC=11.410 IC/col=0.951 n_of_columns=12

specificity:

A |   6   0   0   6   6  24   0   6   0   0   0  78
C |   6   0  96  78  78  24  96   6   0   0  96   6
G |   6  96   0   6   6  24   0  78  96  96   0   6
T |  78   0   0   6   6  24   0   6   0   0   0   6

scan!

home
updated Fri Dec 15 14:18:07 2023