interface graph thumbnail
legend  pdf

structure nameHUMAN RNASE H CATALYTIC DOMAIN MUTANT D210N IN COMPLEX WITH 18-MER RNA/DNA HYBRID
(Ribonuclease H1)
referenceGaidamakov et al. Mol.Cell 28 264 2007
sourceHomo sapiens
experimentX-ray (resolution=2.55, R-factor=?)
structural superfamilyRibonuclease H-like;
sequence familyRNase H;
multimeric complexes2qkb_AB 2qkk_JW 2qkk_NS
reference complex2qkb_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNNQFWS

Estimated binding specificities ?

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# IC=3.851 IC/col=0.550 n_of_columns=7 specificity:   
A |   7   7   0   7  24  24   7
C |   0   8   0   7  24  24  73
G |  66   0  96   9  24  24   7
T |  23  81   0  73  24  24   9
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updated Mon Dec 18 07:12:34 2023