| structure name | CRYSTAL STRUCTURE OF HNF-6ALPHA DNA-BINDING DOMAIN IN COMPLEX WITH THE TTR PROMOTER (Hepatocyte nuclear factor 6) |
| reference | Nishihira et al. Structure 15 75 2007 |
| source | Rattus norvegicus |
| experiment | X-ray (resolution=2.00, R-factor=0.247) |
| structural superfamily | lambda repressor-like DNA-binding domains;Homeodomain-like; |
| sequence family | CUT domain; Homeobox domain; |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | SQTSDRNMNRR |
Estimated binding specificities ?
| readout + contact |  |
A | 10 10 0 0 0 96 53 0 96 C | 2 10 0 0 96 0 21 0 0 G | 10 64 96 0 0 0 12 0 0 T | 74 12 0 96 0 0 10 96 0scan! |
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: HNF-6ALPHA | ||
| CCAAT | PubMed | 2d5v_B(3.07e-03) |
Dendrogram of similar interfaces ?
matrix format--------------------RT--------IAKGNA------ L +-----------------------------2hdd_A ! ------------------------------IA--NA------ ! +4qtr_D ! +-1 --------------------RT--------NT--NAITRG-- +-7 +---------3 +5zjt_B ! ! ! ! --------------------RT--------ITQCNAACRG-- L ! ! +------5 +6a8r_A ! ! ! ! --------------------RA--------ITQTNAMG---- L ! ! ! ! +5zjt_E +-8 +-----------6 +----------2 --------------------RT--------NT--NAIARG-- L ! ! ! +1b72_B ! ! ! ------------------------------NCITNARGRG-- L +-9 ! +-----------------6fqq_E ! ! ! --------------------RT------KTIAQCNA----RT L ! ! +-----------------------------1ig7_A +-10 ! --------------------RT--------NT--NA--RG-- L ! ! +-----------------------------1b8i_B ! ! ----QASTCTSART---------------------------- L +-11 ! +---5j2y_A ! ! +-------------------------4 QTSTNTVTATSTQTRTETTT---------------------- L ! ! +---2r1j_L +-12 ! --------------------RTSTVC--KGDCRG-------- L ! ! +-----------------------------1w0t_A +-13 ! --------------------RA------KGSAQA-------- L ! ! +-----------------------------6j5b_C -14 ! ------------------------RTQT--ITQANAVTKTKT L ! +-----------------------------2ld5_A ! ------------------------------LARTETQT---- L +-----------------------------7m5w_A |
home
updated Tue Dec 19 06:24:11 2023