interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF CSL BOUND TO DNA
(lin-12 And Glp-1 transcriptional regulator)
referenceHendrickson et al. 'Embo 23 3441 2004
sourceCaenorhabditis elegans
experimentX-ray (resolution=2.85, R-factor=0.201)
structural superfamilyDNA-binding protein LAG-1 CSL;p53-like transcription factors;E set domains;
sequence familyBetatrefoil; LAG1, DNA binding; IPT/TIG domain;
reference complex3brd_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureYERSKSQ

Estimated binding specificities ?

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# IC=2.917 IC/col=0.583 n_of_columns=5 specificity:   
A |   0  12  24   0  60
C |   0  60  24  96  12
G |  12  12  24   0  12
T |  84  12  24   0  12
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updated Mon Dec 18 06:09:29 2023