| structure name | HUMAN DNA TOPOISOMERASE I (70 KDA) IN COMPLEX WITH THE POISON CAMPTOTHECIN AND COVALENT COMPLEX WITH A 22 BASE PAIR DNA DUPLEX (DNA topoisomerase I) |
| reference | Staker et al. J.Med.Chem. 48 2336 2005 |
| source | Homo sapiens |
| experiment | X-ray (resolution=3.00, R-factor=0.244) |
| structural superfamily | Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment;DNA breaking-rejoining enzymes;Eukaryotic DNA topoisomerase I, dispensable insert domain; |
| sequence family | Eukaryotic DNA topoisomerase I, DNA bind; Eukaryotic DNA topoisomerase I, catalyti; |
| reference complex | 1a31_A |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | NERKYMKNKN |
Estimated binding specificities ?
| contact |  |
A | 67 9 11 0 C | 9 69 9 0 G | 9 9 9 0 T | 11 9 67 96scan! |
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updated Mon Dec 18 06:07:13 2023