structure name | HUMAN DNA TOPOISOMERASE I (70 KDA) IN COMPLEX WITH THE INDENOISOQUINOLINE MJ-II-38 AND COVALENT COMPLEX WITH A 22 BASE PAIR DNA DUPLEX (DNA topoisomerase I) |
reference | Staker et al. J.Med.Chem. 48 2336 2005 |
source | Homo sapiens |
experiment | X-ray (resolution=3.00, R-factor=?) |
structural superfamily | Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment;DNA breaking-rejoining enzymes;Eukaryotic DNA topoisomerase I, dispensable insert domain; |
sequence family | Eukaryotic DNA topoisomerase I, DNA bind; Eukaryotic DNA topoisomerase I, catalyti; |
reference complex | 1a31_A |
links to other resources | NAKB PDIdb DNAproDB |
protein sequence | |
interface signature | RIKYMNKDN |
Estimated binding specificities ?
contact |
A | 67 9 9 0 C | 9 69 9 0 G | 9 9 9 0 T | 11 9 69 96scan! |
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updated Mon Dec 18 06:03:00 2023