1rtd_CD : 3D-footprint complex

structure name	STRUCTURE OF A CATALYTIC COMPLEX OF HIV-1 REVERSE TRANSCRIPTASE: IMPLICATIONS FOR NUCLEOSIDE ANALOG DRUG RESISTANCE
reference	Harrison et al. Science 282 1669 1998
source	HUMAN IMMUNODEFICIENCY VIRUS 1
experiment	X-ray (resolution=3.20, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	1rtd_B 7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1rtd_C interface=61,74,94,115,157,183,184,258,448,475, kispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvFaikkkdstkwrkLvdfrelnkrtqdfwevqlgIphpaglkkkksvtvldvgdaYfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgsPaifqssmtkilepfrkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiCklvgklnwasqiypgikvrqlckllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepivgaetfyvdgaanRetklgkagyvtnkgrqkvvpltdttnQktqlqaiylalqdsglevnivtdsqyalgiiqaqpdeseselvnqiieqlikkekvylawvpahkgiggneqvdklvsa > 1rtd_D interface= spietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaIkkkdstkwrklvDfrelnkrtqdfwevqlgipHpaglkkkksvtvldvgdayfSvpldedfrkytaftipsinnetpgiryqynvlpqgwkgspaIfqssmtkilepfrkqnpdiviyqymDDlyvgsdleigqhrtkieelrqhllrwglttpgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypGikvrqlckllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyql
interface signature	FLIYPYMCRQ/IDHSIDDG

Estimated binding specificities ?

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# IC=5.787 IC/col=0.322 n_of_columns=18

specificity:

A |   3   0   3  14  24  24  24  24  24  24  24  24  24  24  12  24   0  86
C |  86  96   3  18  24  24  24  24  24  24  24  24  24  24  18  24   0   3
G |   4   0  87  49  24  24  24  24  24  24  24  24  24  24  51  24  96   3
T |   3   0   3  15  24  24  24  24  24  24  24  24  24  24  15  24   0   4

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updated Fri Dec 15 10:54:04 2023