1r0a_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE COVALENTLY TETHERED TO DNA TEMPLATE-PRIMER SOLVED TO 2.8 ANGSTROMS
reference	Arnold et al. J.Virol. 78 3387 2004
source	HUMAN IMMUNODEFICIENCY VIRUS 1
experiment	X-ray (resolution=2.80, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	1r0a_B 7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1r0a_A interface=94,115,157,183,184,356,358,448, pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgIphpaglkkkksvtvldvgdaYfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgsPaifqssmtkilepfkkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndicklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyaRmRgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepivgaetfyvdgaanRetklgkagyvtnkgrqkvvpltnttnqktelqaiylalqdsglevnivtdsqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahkgiggneqvdklvsagirk > 1r0a_B interface= pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgIphpaglkkkksvtvldvgdaYfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgsPaifqssmtkilepfkkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyaRmRgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyql
interface signature	IYPYMRRR/IYPYMRR

Estimated binding specificities ?

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# IC=4.915 IC/col=0.289 n_of_columns=17

specificity:

A |   7   7  24  24  24  24  24   0   7  24  24  24  24  24  24   7   0
C |   9  73  24  24  24  24  24   0  73  24  24  24  24  24  24  73   0
G |   7   9  24  24  24  24  24   0   7  24  24  24  24  24  24   9  96
T |  73   7  24  24  24  24  24  96   9  24  24  24  24  24  24   7   0

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updated Fri Dec 15 10:48:20 2023