interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF TETRACYCLINE REPRESSOR/OPERATOR COMPLEX
(PROTEIN TETRACYCLINE REPRESSOR)
referenceSchnappinger et al. Nat.Struct.Biol. 7 215 2000
sourceEscherichia coli
experimentX-ray (resolution=2.50, R-factor=0.244)
structural superfamilyTetracyclin repressor-like, C-terminal domain;Homeodomain-like;
sequence familyTetracyclin repressor, Cterminal allalpha; Bacterial regulatory proteins, tetR family;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRPTW

Estimated binding specificities ?

contactlogo
# IC=3.142 IC/col=0.786 n_of_columns=4 specificity:   
A |   0  13   0  57
C |  96  54   0  13
G |   0  13   0  13
T |   0  16  96  13
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --RC----PTTC--WC   L                     +-------1qpi_A    
                            +--------------1 
  MTRG--TTMGSCYTYT   L   +--2              +-------3zql_B    
                         !  ! 
  ----SCKGSG--IGYC   L --3  +----------------------2yvh_A    
                         ! 
  TA----ECAC--YCRA       +-------------------------5haw_A    
                       

home
updated Tue Dec 19 06:02:45 2023