interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF E.COLI FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE (FPG) COVALENTLY TRAPPED WITH DNA
(formamidopyrimidine-DNA glycosylase)
referenceFernandes et al. J.Biol.Chem. 277 19811 2002
sourceEscherichia coli
experimentX-ray (resolution=2.10, R-factor=?)
structural superfamilyN-terminal domain of MutM-like DNA repair proteins;S13-like H2TH domain;Glucocorticoid receptor-like DNA-binding domain;
sequence familyFormamidopyrimidineDNA glycosylase N; FormamidopyrimidineDNA glycosylase H2;
multimeric complexes1k82_AB 1k82_CD
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRMRFKDAQR

Estimated binding specificities ?

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# IC=4.434 IC/col=0.887 n_of_columns=5 specificity:   
A |  96   0  96  54  13
C |   0   0   0  13  13
G |   0  96   0  16  54
T |   0   0   0  13  16
scan!

Dendrogram of similar interfaces ?

matrix format
  
  RA--MG----RCFCKGDGACQTRG   L                +-1k82_A    
                                            +-2 
  --RTMT----RCFA--------RT         +--------4 +-6fl1_A    
                                   !        ! 
  RT--MG----RCFC--------RT   L     !        +---6tc9_A    
                                 +-6 
  --RGMG----RCFC--------RG   L   ! !            +3u6p_A    
                                 ! !          +-1 
  --RA------RGFT--------RA       ! +----------3 +3gpu_A    
                               --7            ! 
  --QALGYA--------------RG       !            +-1k3x_A    
                                 ! 
  ----MG----RGFG--------RG       !     +--------3twm_A    
                                 +-----5 
  ----MG--ITRCFG----HG--RG   L         +--------5itu_A

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updated Tue Dec 19 05:49:24 2023