1ic8_AB : 3D-footprint complex

structure name	HEPATOCYTE NUCLEAR FACTOR 1A BOUND TO DNA : MODY3 GENE PRODUCT
reference	Dhe-Paganon et al. Mol.Cell 10 1129 2002
source	Homo sapiens
experiment	X-ray (resolution=2.60, R-factor=?)
structural superfamily	lambda repressor-like DNA-binding domains;Homeodomain-like;
reference complex	1ic8_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1ic8_A interface=54,55,56,57,59,60,67,159,160,164,167, kelenlspeeaahqkavvetllqedpwrvakmvksylqqhnipqrevvdttglNQSHlSQhlnkgtPmktqkraalytwyvrkqrevaqqftharnrfkwgpasqqilfqayerqknpskeeretlveecnraeciqrgvspsqaqglgsnlvtevrvYNwfaNrrKeea > 1ic8_B interface=56,57,58,59,61,62,68,69,98,160,161,164,165,168, ilkelenlspeeaahqkavvetllqedpwrvakmvksylqqhnipqrevvdttglNQSHlSQhlnkgTPmktqkraalytwyvrkqrevaqqfthrnRfkwgpasqqilfqayerqknpskeeretlveecnraeciqrgvspsqaqglgsnlvtevrvYNwfANrrKeeafr
interface signature	NQSHSQPYNNK/NQSHSQTPRYNANK

Estimated binding specificities ?

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# IC=17.596 IC/col=1.035 n_of_columns=17

specificity:

A |   0   0   0   0  92  29   0   0  91   0   6  96  96   6   0  80  61
C |   0   0  36   0   0   4   0   0   0   0   9   0   0  79  96   6   9
G |  96  96   6  96   2  61   0   0   0   0  13   0   0   9   0   8  18
T |   0   0  54   0   2   2  96  96   5  96  68   0   0   2   0   2   8

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updated Fri Dec 15 09:12:13 2023