DNA Binding Motif

Accessions: 6chv_BD (3D-footprint 20231221)
Names: Antitoxin HigA
Organisms: Proteus vulgaris
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Proteus vulgaris HigA antitoxin bound to DNA
Length: 16
Consensus: TACAnnnnnTGTannA
Weblogo:
PSSM: P0 A C G T
01 19 0 8 69 T
02 96 0 0 0 A
03 0 96 0 0 C
04 96 0 0 0 A
05 24 24 24 24 n
06 24 24 24 24 n
07 24 24 24 24 n
08 24 24 24 24 n
09 24 24 24 24 n
10 0 0 0 96 T
11 0 0 96 0 G
12 0 0 0 96 T
13 61 8 17 10 a
14 24 24 24 24 n
15 24 24 24 24 n
16 72 8 8 8 A
Type: Heterodimer
Binding TFs: 6chv_B (Helix-turn-helix)
6chv_D (Helix-turn-helix)
Binding Sites: 6chv_E
6chv_F
Publications: Schureck MA, Meisner J, Hoffer ED, Wang D, Onuoha N, Ei Cho S, Lollar P 3rd, Dunham CM. Structural basis of transcriptional regulation by the HigA antitoxin. Mol Microbiol 111:1449-1462 (2019). [Pubmed]

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